Use of hybridization kinetics for differentiating specific from non-specific binding to oligonucleotide microarrays
Hybridization kinetics were found to be significantly different for specific and non-specific binding of labeled cRNA to surface-bound oligonucleotides on microarrays. We show direct evidence that in a complex sample specific binding takes longer to reach hybridization equilibrium than the non- spec...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12177314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf085 |
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