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Use of hybridization kinetics for differentiating specific from non-specific binding to oligonucleotide microarrays

Hybridization kinetics were found to be significantly different for specific and non-specific binding of labeled cRNA to surface-bound oligonucleotides on microarrays. We show direct evidence that in a complex sample specific binding takes longer to reach hybridization equilibrium than the non- spec...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nucleic Acids Res
Principais autores: Dai, Hongyue, Meyer, Michael, Stepaniants, Sergey, Ziman, Michael, Stoughton, Roland
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2002
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12177314/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf085
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