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Use of hybridization kinetics for differentiating specific from non-specific binding to oligonucleotide microarrays

Hybridization kinetics were found to be significantly different for specific and non-specific binding of labeled cRNA to surface-bound oligonucleotides on microarrays. We show direct evidence that in a complex sample specific binding takes longer to reach hybridization equilibrium than the non- spec...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Dai, Hongyue, Meyer, Michael, Stepaniants, Sergey, Ziman, Michael, Stoughton, Roland
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2002
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC134259/
https://ncbi.nlm.nih.gov/pubmed/12177314
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