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Advanced method for oligonucleotide deprotection

A new procedure for rapid deprotection of synthetic oligodeoxynucleotides has been developed. While all known deprotection methods require purification to remove the residual protective groups (e.g. benzamide) and insoluble silicates, the new procedure based on the use of an ammonia-free reagent mix...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Surzhikov, Sergey A., Timofeev, Edward N., Chernov, Boris K., Golova, Julia B., Mirzabekov, Andrei D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102833/
https://ncbi.nlm.nih.gov/pubmed/10734206
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