The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis

Class Ia phosphatidylinositol 3 kinase (PI3K) is required for oncogenic receptor-mediated transformation; however, the individual roles of the two commonly expressed class Ia PI3K isoforms in oncogenic receptor signaling have not been elucidated in vivo. Here, we show that genetic ablation of p110α...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Utermark, Tamara, Rao, Trisha, Cheng, Hailing, Wang, Qi, Lee, Sang Hyun, Wang, Zhigang C., Iglehart, J. Dirk, Roberts, Thomas M., Muller, William J., Zhao, Jean J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2012
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404385/
https://ncbi.nlm.nih.gov/pubmed/22802530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.191973.112
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller