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The p110δ isoform of PI 3-kinase negatively controls RhoA and PTEN
Inactivation of PI 3-kinase (PI3K) signalling is critical for tumour suppression by PTEN. This is thought to be a unidirectional relationship in which PTEN degrades the lipids produced by PI3K, thus controlling cell proliferation, survival and migration. We now show that this relationship is in fact...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914109/ https://ncbi.nlm.nih.gov/pubmed/17581634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601763 |
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