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p110δ PI3 kinase pathway: emerging roles in cancer
Class IA PI3Ks consists of three isoforms of the p110 catalytic subunit designated p110α, p110β, and p110δ which are encoded by three separate genes. Gain-of-function mutations on PIK3CA gene encoding for p110α isoform have been detected in a wide variety of human cancers whereas no somatic mutation...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585436/ https://ncbi.nlm.nih.gov/pubmed/23459844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00040 |
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