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Truncated Title: p110 isoforms in cancer

Activation of the PI3K signaling pathway is frequently found in common human cancers, brought about by oncogenic RTKs acting upstream, PTEN loss, or activating mutations of PI3K itself. Recent studies have delineated distinct but overlapping functions in cell signaling and tumorigenesis for p110α an...

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Detalhes bibliográficos
Main Authors: Jia, Shidong, Roberts, Thomas M., Zhao, Jean J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142565/
https://ncbi.nlm.nih.gov/pubmed/19200708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.12.007
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