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Truncated Title: p110 isoforms in cancer
Activation of the PI3K signaling pathway is frequently found in common human cancers, brought about by oncogenic RTKs acting upstream, PTEN loss, or activating mutations of PI3K itself. Recent studies have delineated distinct but overlapping functions in cell signaling and tumorigenesis for p110α an...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3142565/ https://ncbi.nlm.nih.gov/pubmed/19200708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.12.007 |
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