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IL-21 is critical for graft-versus-host disease in a mouse model
Immunological effects of IL-21 on T-, B-, and NK-cells have been reported, but the role for IL-21 in graft-versus-host disease (GVHD) remains obscure. Here we demonstrate that morbidity and mortality of GVHD was significantly reduced after bone marrow transplantation with splenocytes from IL-21R(−/−...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3403836/ https://ncbi.nlm.nih.gov/pubmed/19718060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2009.223 |
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