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Substrate-Ligand Interactions in Geobacillus Stearothermophilus Nitric Oxide Synthase()
Ntric oxide synthase (NOS) generates NO via a sequential two-step reaction, L-arginine (L-Arg) → N-hydroxy-L-arginine (NOHA) → L-citrulline + NO. Each step of the reaction follows a distinct mechanism defined by the chemical environment introduced by each substrate bound to the heme active site. The...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3403685/ https://ncbi.nlm.nih.gov/pubmed/18956884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801491e |
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