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Sequence-dependent backbone dynamics of a viral fusogen transmembrane helix

The transmembrane domains of membrane fusogenic proteins are known to contribute to lipid bilayer mixing as indicated by mutational studies and functional reconstitution of peptide mimics. Here, we demonstrate that mutations of a GxxxG motif or of Ile residues, that were previously shown to compromi...

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Hlavní autoři: Stelzer, Walter, Langosch, Dieter
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403448/
https://ncbi.nlm.nih.gov/pubmed/22593029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2094
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