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Sequence-Specific Conformational Flexibility of SNARE Transmembrane Helices Probed by Hydrogen/Deuterium Exchange

SNARE proteins mediate fusion of intracellular eukaryotic membranes and their α-helical transmembrane domains are known to contribute to lipid bilayer mixing. Synthetic transmembrane domain peptides were previously shown to mimic the function of SNARE proteins in that they trigger liposome fusion in...

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Detalles Bibliográficos
Main Authors: Stelzer, Walter, Poschner, Bernhard C., Stalz, Holger, Heck, Albert J., Langosch, Dieter
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2479619/
https://ncbi.nlm.nih.gov/pubmed/18456822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.132928
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