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Sequence-Specific Conformational Flexibility of SNARE Transmembrane Helices Probed by Hydrogen/Deuterium Exchange
SNARE proteins mediate fusion of intracellular eukaryotic membranes and their α-helical transmembrane domains are known to contribute to lipid bilayer mixing. Synthetic transmembrane domain peptides were previously shown to mimic the function of SNARE proteins in that they trigger liposome fusion in...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2479619/ https://ncbi.nlm.nih.gov/pubmed/18456822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.132928 |
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