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Stabilization of conformationally dynamic helices by covalently attached acyl chains

Acylation of proteins is known to mediate membrane attachment and to influence subcellular sorting. Here, we report that acylation can stabilize secondary structure. Circular dichroism spectroscopy showed that N-terminal attachment of acyl chains decreases the ability of an intrinsically flexible hy...

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Detalhes bibliográficos
Main Authors: Poschner, Bernhard C, Langosch, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776967/
https://ncbi.nlm.nih.gov/pubmed/19569191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.155
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