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Sequence-dependent backbone dynamics of a viral fusogen transmembrane helix

The transmembrane domains of membrane fusogenic proteins are known to contribute to lipid bilayer mixing as indicated by mutational studies and functional reconstitution of peptide mimics. Here, we demonstrate that mutations of a GxxxG motif or of Ile residues, that were previously shown to compromi...

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Autori principali: Stelzer, Walter, Langosch, Dieter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Subscription Services, Inc., A Wiley Company 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403448/
https://ncbi.nlm.nih.gov/pubmed/22593029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2094
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