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Mechanism of zinc-mediated inhibition of caspase-9
Zinc-mediated inhibition is implicated in global caspase regulation, with relief of zinc-mediated inhibition central to both small-molecule and natively induced caspase activation. As an initiator, caspase-9 regulates the upstream stages of the apoptotic caspase cascade, making it a critical control...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3403442/ https://ncbi.nlm.nih.gov/pubmed/22573662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2090 |
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