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Mechanism of zinc-mediated inhibition of caspase-9

Zinc-mediated inhibition is implicated in global caspase regulation, with relief of zinc-mediated inhibition central to both small-molecule and natively induced caspase activation. As an initiator, caspase-9 regulates the upstream stages of the apoptotic caspase cascade, making it a critical control...

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Detalhes bibliográficos
Main Authors: Huber, Kristen L, Hardy, Jeanne A
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403442/
https://ncbi.nlm.nih.gov/pubmed/22573662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2090
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