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Inhibition of caspase-9 by stabilized peptides targeting the dimerization interface
Caspases comprise a family of dimeric cysteine proteases that control apoptotic programmed cell death and are therefore critical in both organismal development and disease. Specific inhibition of individual caspases has been repeatedly attempted, but has not yet been attained. Caspase-9 is an upstre...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544179/ https://ncbi.nlm.nih.gov/pubmed/23203690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22080 |
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