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Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats
Seizure susceptibility to neurological insults, including chemical convulsants, is age-dependent and most likely reflective of overall differences in brain excitability. The molecular and cellular mechanisms underlying development-dependent seizure susceptibility remain to be fully understood. Becau...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402618/ https://ncbi.nlm.nih.gov/pubmed/22613737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.05.003 |
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