Seizure-dependent mTOR activation in 5-HT neurons promotes autism-like behaviors in mice

Epilepsy and autism spectrum disorder (ASD) are common comorbidities of one another. Despite the prevalent correlation between the two disorders, few studies have been able to elucidate a mechanistic link. We demonstrate that forebrain specific Tsc1 deletion in mice causes epilepsy and autism-like b...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurobiol Dis
Egile Nagusiak: McMahon, John J., Yu, Wilson, Yang, Jun, Feng, Haihua, Helm, Meghan, McMahon, Elizabeth, Zhu, Xinjun, Shin, Damian, Huang, Yunfei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394017/
https://ncbi.nlm.nih.gov/pubmed/25315683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.10.004
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