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Delivery of chemo-sensitizing siRNAs to HER2(+)-breast cancer cells using RNA aptamers
Human epidermal growth factor receptor 2 (HER2) expression in breast cancer is associated with an aggressive phenotype and poor prognosis, making it an appealing therapeutic target. Trastuzumab, an HER2 antibody-based inhibitor, is currently the leading targeted treatment for HER2(+)-breast cancers....
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401474/ https://ncbi.nlm.nih.gov/pubmed/22467215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks294 |
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