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Mixture of differentially tagged Tol2 transposons accelerates conditional disruption of a broad spectrum of genes in mouse embryonic stem cells

Among the insertional mutagenesis techniques used in the current international knockout mouse project (KOMP) on the inactivation of all mouse genes in embryonic stem (ES) cells, random gene trapping has been playing a major role. Gene-targeting experiments have also been performed to individually an...

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Autors principals: Mayasari, N. Ika, Mukougawa, Keiko, Shigeoka, Toshiaki, Kawakami, Koichi, Kawaichi, Masashi, Ishida, Yasumasa
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401447/
https://ncbi.nlm.nih.gov/pubmed/22447447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks262
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