Mixture of differentially tagged Tol2 transposons accelerates conditional disruption of a broad spectrum of genes in mouse embryonic stem cells

Among the insertional mutagenesis techniques used in the current international knockout mouse project (KOMP) on the inactivation of all mouse genes in embryonic stem (ES) cells, random gene trapping has been playing a major role. Gene-targeting experiments have also been performed to individually an...

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Detalles Bibliográficos
Autores principales: Mayasari, N. Ika, Mukougawa, Keiko, Shigeoka, Toshiaki, Kawakami, Koichi, Kawaichi, Masashi, Ishida, Yasumasa
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401447/
https://ncbi.nlm.nih.gov/pubmed/22447447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks262
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