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Suppression of nonsense-mediated mRNA decay permits unbiased gene trapping in mouse embryonic stem cells
An international collaborative project has been proposed to inactivate all mouse genes in embryonic stem (ES) cells using a combination of random and targeted insertional mutagenesis techniques. Random gene trapping will be the first choice in the initial phase, and gene-targeting experiments will t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548380/ https://ncbi.nlm.nih.gov/pubmed/15687378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni022 |
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