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Mixture of differentially tagged Tol2 transposons accelerates conditional disruption of a broad spectrum of genes in mouse embryonic stem cells

Among the insertional mutagenesis techniques used in the current international knockout mouse project (KOMP) on the inactivation of all mouse genes in embryonic stem (ES) cells, random gene trapping has been playing a major role. Gene-targeting experiments have also been performed to individually an...

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Detalhes bibliográficos
Main Authors: Mayasari, N. Ika, Mukougawa, Keiko, Shigeoka, Toshiaki, Kawakami, Koichi, Kawaichi, Masashi, Ishida, Yasumasa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401447/
https://ncbi.nlm.nih.gov/pubmed/22447447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks262
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