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Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function
Themis1, a recently identified T cell protein, has a critical function in the generation of mature CD4(+)CD8(−) and CD4(−)CD8(+) (CD4- and CD8- single positive; SP) thymocytes and T cells. Although Themis1 has been shown to bind to the adapter proteins LAT and Grb2, previous studies have yielded con...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401357/ https://ncbi.nlm.nih.gov/pubmed/22732588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200123 |
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