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THEMIS, a new T cell specific protein important for late thymocyte development
During positive selection, thymocytes transition through a stage during which T cell receptor (TCR) signaling controls CD4 versus CD8 lineage choice and subsequent maturation. Here, we describe a new T cell specific protein, THEMIS, that performs a distinct function during this stage. In Themis(-/-)...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848698/ https://ncbi.nlm.nih.gov/pubmed/19597498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1768 |
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