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Computational and experimental studies of the interaction between phosphopeptides and the C-terminal domain of BRCA1
The C-terminal domain of BRCA1 (BRCT) is involved in the DNA repair pathway by recognizing the pSXXF motif in interacting proteins. It has been reported that short peptides containing this motif bind to BRCA1(BRCT) in the micromolar range with high specificity. In this work, the binding of pSXXF pep...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400539/ https://ncbi.nlm.nih.gov/pubmed/22086652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-011-9484-3 |
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