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Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids.
We have analyzed the chromatin structure of the human beta-globin locus in somatic cell hybrids resulting from the fusion of human non-erythroid cells and mouse erythroleukemia (MEL) cells. In these hybrids, the human adult beta-globin gene, but neither the embryonic nor fetal globin genes, is activ...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1987
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC339937/ https://ncbi.nlm.nih.gov/pubmed/3480506 |
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