Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids.
We have analyzed the chromatin structure of the human beta-globin locus in somatic cell hybrids resulting from the fusion of human non-erythroid cells and mouse erythroleukemia (MEL) cells. In these hybrids, the human adult beta-globin gene, but neither the embryonic nor fetal globin genes, is activ...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1987
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3480506/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.24.10159 |
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