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High-level beta-globin expression after retroviral transfer of locus activation region-containing human beta-globin gene derivatives into murine erythroleukemia cells.

The locus activation region (LAR) of the human beta-globin-like gene cluster is characterized by a group of four DNase I hypersensitive sites, which arise specifically in erythroid tissues and are required for a normal pattern of beta-globin-like gene expression. The hypersensitive sites are found a...

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Bibliografski detalji
Glavni autori: Novak, U, Harris, E A, Forrester, W, Groudine, M, Gelinas, R
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC53905/
https://ncbi.nlm.nih.gov/pubmed/2333288
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