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Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids.

We have analyzed the chromatin structure of the human beta-globin locus in somatic cell hybrids resulting from the fusion of human non-erythroid cells and mouse erythroleukemia (MEL) cells. In these hybrids, the human adult beta-globin gene, but neither the embryonic nor fetal globin genes, is activ...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Forrester, W C, Takegawa, S, Papayannopoulou, T, Stamatoyannopoulos, G, Groudine, M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1987
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC339937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3480506/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.24.10159
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