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Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids.

We have analyzed the chromatin structure of the human beta-globin locus in somatic cell hybrids resulting from the fusion of human non-erythroid cells and mouse erythroleukemia (MEL) cells. In these hybrids, the human adult beta-globin gene, but neither the embryonic nor fetal globin genes, is activ...

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Bibliografiset tiedot
Päätekijät: Forrester, W C, Takegawa, S, Papayannopoulou, T, Stamatoyannopoulos, G, Groudine, M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1987
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC339937/
https://ncbi.nlm.nih.gov/pubmed/3480506
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