Sequence and structure relationships within von Willebrand factor

In the present study, we re-annotated von Willebrand factor (VWF), assigned its entire sequence to specific modules, and related these modules to structure using electron microscopy (EM). The D domains are assemblies of smaller modules visible as lobes in EM. Modules in the D-domain assemblies inclu...

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Autores principales: Zhou, Yan-Feng, Eng, Edward T., Zhu, Jieqing, Lu, Chafen, Walz, Thomas, Springer, Timothy A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398765/
https://ncbi.nlm.nih.gov/pubmed/22490677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-405134
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