लोड हो रहा है...
Highly reinforced structure of a C-terminal dimerization domain in von Willebrand factor
The C-terminal cystine knot (CK) (CTCK) domain in von Willebrand factor (VWF) mediates dimerization of proVWF in the endoplasmic reticulum and is essential for long multimers required for hemostatic function. The CTCK dimer crystal structure reveals highly elongated monomers with 2 β-ribbons and 4 i...
में बचाया:
| मुख्य लेखकों: | , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society of Hematology
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962159/ https://ncbi.nlm.nih.gov/pubmed/24394662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-523639 |
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