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N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells
There is evidence suggesting that N-cadherin expression on osteoblast lineage cells regulates hematopoietic stem cell (HSC) function and quiescence. To test this hypothesis, we conditionally deleted N-cadherin (Cdh2) in osteoblasts using Cdh2(flox/flox) Osx-Cre mice. N-cadherin expression was effici...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3398761/ https://ncbi.nlm.nih.gov/pubmed/22323481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-377457 |
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