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Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells

Hematopoietic stem cell (HSC) regulation is highly dependent on interactions with the marrow microenvironment. Controversy exists on N-cadherin's role in support of HSCs. Specifically, it is unknown whether microenvironmental N-cadherin is required for normal marrow microarchitecture and for he...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bromberg, Olga, Frisch, Benjamin J., Weber, Jonathan M., Porter, Rebecca L., Civitelli, Roberto, Calvi, Laura M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398755/
https://ncbi.nlm.nih.gov/pubmed/22596259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-377853
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