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Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells

Hematopoietic stem cell (HSC) regulation is highly dependent on interactions with the marrow microenvironment. Controversy exists on N-cadherin's role in support of HSCs. Specifically, it is unknown whether microenvironmental N-cadherin is required for normal marrow microarchitecture and for he...

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Autori principali: Bromberg, Olga, Frisch, Benjamin J., Weber, Jonathan M., Porter, Rebecca L., Civitelli, Roberto, Calvi, Laura M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398755/
https://ncbi.nlm.nih.gov/pubmed/22596259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-377853
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