Osteoblastic expansion induced by parathyroid hormone receptor signaling in murine osteocytes is not sufficient to increase hematopoietic stem cells

Microenvironmental expansion of hematopoietic stem cells (HSCs) is induced by treatment with parathyroid hormone (PTH) or activation of the PTH receptor (PTH1R) in osteoblastic cells; however, the osteoblastic subset mediating this action of PTH is unknown. Osteocytes are terminally differentiated o...

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Detalhes bibliográficos
Main Authors: Calvi, Laura M., Bromberg, Olga, Rhee, Yumie, Weber, Jonathan M., Smith, Julianne N. P., Basil, Miles J., Frisch, Benjamin J., Bellido, Teresita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311272/
https://ncbi.nlm.nih.gov/pubmed/22262765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-360933
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