In Silico and In Vitro Comparison of HIV-1 Subtypes B and CRF02_AG Integrases Susceptibility to Integrase Strand Transfer Inhibitors

Most antiretroviral medical treatments were developed and tested principally on HIV-1 B nonrecombinant strain, which represents less than 10% of the worldwide HIV-1-infected population. HIV-1 circulating recombinant form CRF02_AG is prevalent in West Africa and is becoming more frequent in other cou...

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Main Authors: Ni, Xiaoju, Abdel-Azeim, Safwat, Laine, Elodie, Arora, Rohit, Osemwota, Osamuede, Marcelin, Anne-Geneviève, Calvez, Vincent, Mouscadet, Jean-François, Tchertanov, Luba
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398581/
https://ncbi.nlm.nih.gov/pubmed/22829822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/548657
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