Alleviation of Gut Inflammation by Cdx2/Pxr Pathway in a Mouse Model of Chemical Colitis

Pregnane X Receptor (PXR), a master regulator of drug metabolism and inflammation, is abundantly expressed in the gastrointestinal tract. Baicalein and its O-glucuronide baicalin are potent anti-inflammatory and anti-cancer herbal flavonoids that undergo a complex cycle of interconversion in the liv...

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Hauptverfasser: Dou, Wei, Mukherjee, Subhajit, Li, Hao, Venkatesh, Madhukumar, Wang, Hongwei, Kortagere, Sandhya, Peleg, Ariel, Chilimuri, Sridhar S., Wang, Zheng-Tao, Feng, Ying, Fearon, Eric R., Mani, Sridhar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398007/
https://ncbi.nlm.nih.gov/pubmed/22815676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036075
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