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Chrysin Ameliorates Chemically Induced Colitis in the Mouse through Modulation of a PXR/NF-κB Signaling Pathway

Targeted activation of pregnane X receptor (PXR) in recent years has become a therapeutic strategy for inflammatory bowel disease. Chrysin is a naturally occurring flavonoid with anti-inflammation activity. The current study investigated the role of chrysin as a putative mouse PXR agonist in prevent...

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Detalhes bibliográficos
Main Authors: Dou, Wei, Zhang, Jingjing, Zhang, Eryun, Sun, Aning, Ding, Lili, Chou, Guixin, Wang, Zhengtao, Mani, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657113/
https://ncbi.nlm.nih.gov/pubmed/23536316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.201863
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