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Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway

Isorhamnetin is an O-methylated flavonol present in fruit and vegetables. We recently reported the identification of isorhamnetin as an activator of the human pregnane X receptor (PXR), a known target for abrogating inflammation in inflammatory bowel disease (IBD). The current study investigated the...

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Detalhes bibliográficos
Main Authors: Dou, Wei, Zhang, Jingjing, Li, Hao, Kortagere, Sandhya, Sun, Katherine, Ding, Lili, Ren, Gaiyan, Wang, Zhengtao, Mani, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125479/
https://ncbi.nlm.nih.gov/pubmed/24913217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2014.04.006
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