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The Role of Activity in Synaptic Degeneration in a Protein Misfolding Disease, Prion Disease
In chronic neurodegenerative diseases associated with aggregates of misfolded proteins (such as Alzheimer's, Parkinson's and prion disease), there is an early degeneration of presynaptic terminals prior to the loss of the neuronal somata. Identifying the mechanisms that govern synapse dege...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397974/ https://ncbi.nlm.nih.gov/pubmed/22815961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041182 |
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