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The Role of Activity in Synaptic Degeneration in a Protein Misfolding Disease, Prion Disease

In chronic neurodegenerative diseases associated with aggregates of misfolded proteins (such as Alzheimer's, Parkinson's and prion disease), there is an early degeneration of presynaptic terminals prior to the loss of the neuronal somata. Identifying the mechanisms that govern synapse dege...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Caleo, Matteo, Restani, Laura, Vannini, Eleonora, Siskova, Zuzana, Al-Malki, Hussain, Morgan, Ruth, O'Connor, Vincent, Perry, V. Hugh
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397974/
https://ncbi.nlm.nih.gov/pubmed/22815961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041182
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