Degenerating Synaptic Boutons in Prion Disease : Microglia Activation without Synaptic Stripping

A growing body of evidence suggests that the loss of synapses is an early and major component of a number of neurodegenerative diseases. Murine prion disease offers a tractable preparation in which to study synaptic loss in a chronic neurodegenerative disease and to explore the underlying mechanisms...

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Bibliographic Details
Main Authors: Šišková, Zuzana, Page, Anton, O’Connor, Vincent, Perry, Victor Hugh
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2009
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751557/
https://ncbi.nlm.nih.gov/pubmed/19779137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090372
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