Morphological and Functional Abnormalities in Mitochondria Associated with Synaptic Degeneration in Prion Disease

Synaptic and dendritic pathology is a well-documented component of prion disease. In common with other neurodegenerative diseases that contain an element of protein misfolding, little is known about the underlying mechanisms of synaptic degeneration. In particular, in prion disease the relationship...

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Bibliographic Details
Main Authors: Sisková, Zuzana, Mahad, Don Joseph, Pudney, Carianne, Campbell, Graham, Cadogan, Mark, Asuni, Ayodeji, O'Connor, Vincent, Perry, Victor Hugh
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928973/
https://ncbi.nlm.nih.gov/pubmed/20651247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091037
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