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Myosin Regulatory Light Chain Diphosphorylation Slows Relaxation of Arterial Smooth Muscle
The principal signal to activate smooth muscle contraction is phosphorylation of the regulatory light chains of myosin (LC(20)) at Ser(19) by Ca(2+)/calmodulin-dependent myosin light chain kinase. Inhibition of myosin light chain phosphatase leads to Ca(2+)-independent phosphorylation at both Ser(19...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397833/ https://ncbi.nlm.nih.gov/pubmed/22661704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.371609 |
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