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Cross-talk between Rho-associated Kinase and Cyclic Nucleotide-dependent Kinase Signaling Pathways in the Regulation of Smooth Muscle Myosin Light Chain Phosphatase

Ca(2+) sensitization of smooth muscle contraction depends upon the activities of protein kinases, including Rho-associated kinase, that phosphorylate the myosin phosphatase targeting subunit (MYPT1) at Thr(697) and/or Thr(855) (rat sequence numbering) to inhibit phosphatase activity and increase con...

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Detalhes bibliográficos
Main Authors: Grassie, Michael E., Sutherland, Cindy, Ulke-Lemée, Annegret, Chappellaz, Mona, Kiss, Enikö, Walsh, Michael P., MacDonald, Justin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476302/
https://ncbi.nlm.nih.gov/pubmed/22948155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.398479
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