The involvement of myosin regulatory light chain diphosphorylation in sustained vasoconstriction under pathophysiological conditions

Smooth muscle contraction is activated primarily by phosphorylation at Ser19 of the regulatory light chain subunits (LC(20)) of myosin II, catalysed by Ca(2+)/calmodulin-dependent myosin light chain kinase. Ca(2+)-independent contraction can be induced by inhibition of myosin light chain phosphatase...

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Detalles Bibliográficos
Publicado en:J Smooth Muscle Res
Autores principales: Takeya, Kosuke, Wang, Xuemei, Sutherland, Cindy, Kathol, Iris, Loutzenhiser, Kathy, Loutzenhiser, Rodger D., Walsh, Michael P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Japan Society of Smooth Muscle Research 2014
Materias:
Invited Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137258/
https://ncbi.nlm.nih.gov/pubmed/24770446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1540/jsmr.50.18
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