The involvement of myosin regulatory light chain diphosphorylation in sustained vasoconstriction under pathophysiological conditions

Smooth muscle contraction is activated primarily by phosphorylation at Ser19 of the regulatory light chain subunits (LC(20)) of myosin II, catalysed by Ca(2+)/calmodulin-dependent myosin light chain kinase. Ca(2+)-independent contraction can be induced by inhibition of myosin light chain phosphatase...

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Detalhes bibliográficos
Publicado no:J Smooth Muscle Res
Main Authors: Takeya, Kosuke, Wang, Xuemei, Sutherland, Cindy, Kathol, Iris, Loutzenhiser, Kathy, Loutzenhiser, Rodger D., Walsh, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Japan Society of Smooth Muscle Research 2014
Assuntos:
Invited Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137258/
https://ncbi.nlm.nih.gov/pubmed/24770446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1540/jsmr.50.18
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