Rho-kinase mediates diphosphorylation of myosin regulatory light chain in cultured uterine, but not vascular smooth muscle cells

Phosphorylation of myosin regulatory light chain (RLC) triggers contraction in smooth muscle myocytes. Dephosphorylation of phosphorylated RLC (pRLC) is mediated by myosin RLC phosphatase (MLCP), which is negatively regulated by rho-associated kinase (ROK). We have compared basal and stimulated conc...

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Publicat a:J Cell Mol Med
Autors principals: Aguilar, Hector N, Tracey, Curtis N, Zielnik, Barbara, Mitchell, Bryan F
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2012
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393726/
https://ncbi.nlm.nih.gov/pubmed/22947248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2012.01625.x
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